Scientists from the Salk Institute and the University of Virginia have shown that targeted enhancement of pleiotrophins in astrocytes can improve synaptic plasticity and hippocampal function in a mouse model of Down syndrome, suggesting a new gene or protein therapy strategy that could one day facilitate learning and memory.
A new electrochemical method of bubble formation directly on transparent electrodes gently separates cells from substrates without enzymes and toxic coatings. This reduces fouling, prolongs work without downtime and accelerates the cultivation of microalgae for CO2 capture and the production of cell therapies and biological drugs.
A new interdisciplinary study shows that early hominids were exposed to lead millions of years before mining and that a tiny change in the NOVA1 gene could have mitigated neurotoxic effects. This, according to the authors, opened a space in Homo sapiens for the development of complex language and greater social cohesion.
SpectroGen introduces generative AI that from one spectrum (e.g. IR) creates reliable “virtual” Raman and XRD signatures, dramatically accelerating quality control. Factories and laboratories get faster decisions, lower costs and greater measurement coverage, with physics-based models and clear application limits.
Mit physicists have developed a global phase spectroscopy technique that reduces quantum noise and stabilizes the laser oscillator in optical atomic clocks. The method, demonstrated in itterbia, doubles the resolution of measurements and opens the way to stable, portable clocks for geoscience, communications and fundamental physics.
A decline in fertility is not just a story about eggs: the ovary plays a crucial role as an ecosystem of nerves, glia, blood vessels and fibroblasts that change the maturation of follicles over the years. New 3D imaging and unicellular analyses reveal uneven oocyte distribution, denser innervation, and early fibrosis, which explains faster aging and paves the way for more accurate therapies and reserve assessment (AMH)