Science A decline in fertility is not just a story about eggs: the ovary plays a crucial role as an ecosystem of nerves, glia, blood vessels and fibroblasts that change the maturation of follicles over the years. New 3D imaging and unicellular analyses reveal uneven oocyte distribution, denser innervation, and early fibrosis, which explains faster aging and paves the way for more accurate therapies and reserve assessment (AMH)